Clinical Program Courses - PharmD
PT 101 - Pharmacy Orientation: (1+0)
This is a course to acquaint the beginning pharmacy student with the
multiple aspects of the profession of pharmacy, including the mission
of pharmacy, role of pharmacist in society and pharmacy careers,
classification of medications, interpretation of prescriptions and
medication orders, general dispensing procedure and factors affecting
drug dosage, sources of drugs, different dosage forms and various
routes of administration. In addition to the history of pharmacy
practice in various civilizations
PT 202 - Physical Pharmacy: (2+1)
This course provides students with knowledge of physical and
chemical principles essential for the design and formulation of
pharmaceutical products. Students are introduced to the fundamental
concepts of states of matter, Phase equilibrium, colligative properties,
isotonicity solubility, dissolution, partition coefficient, surface and
interfacial phenomena, surface active agents, adsorption and its
application in pharmacy and rheological behaviour of dosage forms
PT303 - Pharmaceutical Dosage Forms I: (2+1)
This course is a study of the system of weights, measures,
mathematical expertise and pharmaceutical calculations requisite to
the compounding, dispensing, and utilization of drugs in pharmacy
practice. It is also concerned with all manufacturing formulations
aspects, packaging, storage and stability of liquid dosage forms
including solutions (aqueous and non-aqueous), suspensions,
emulsions and colloids with emphasis on the technology and pharmaceutical rationale fundamental to their design and development.
The incompatibilities occurring during dispensing are also considered.
PT 404 - Pharmaceutical Dosage Forms II: (2+1)
This course covers the structure and function of the skin, target area of
treatment after topical application to skin, basic principles of diffusion
through membranes and factors affecting percutaneous absorption,
enhancement of skin penetration, transdermal drug delivery systems
(TDDS). It also describes the principles and techniques involved in the
formulation and manufacturing of traditional dermatological semisolid
dosage forms (creams, ointments, gels and pastes ) and cosmetic
products.
PT 505 - Pharmaceutical Dosage Forms III: (2+1)
The course introduces the students to the kinetics of drug
decomposition including rate and order of the reaction, determination
of the half-life, expiry date and shelf-life by different methods,
stability testing, and in-vitro possible drug/excipients interactions. It
also describes the principles and techniques involved in the
formulation, and manufacturing of solid dosage forms including
powders, granules, tablets, capsules and suppositories.
PT 606 - Pharmaceutical Technology : (2+1)
The course provides students with an introduction to industrial
pharmacy. It deals with the principles of various unit operations
such as heat transfer, evaporation, drying, distillation, filtration,
centrifugation, crystallization, extraction, size reduction, size
separation, size analysis and size enlargement. It focuses on the
application of these unit operations in pharmaceutical industry
with emphasis on the equipment and machines used during the
production of different dosage forms.
PT 707 - Advanced Drug Delivery Systems: (1+1)
A continued study of pharmaceutical dosage forms with emphasis on
novel and targeted drug delivery systems. Discussions focusing on
transforming proteins, genes, and other biotechnology driven
compounds into therapeutic products including the role of molecularmodeling and new drug therapies in fabricating rational drug delivery
systems are included.
The course covers targeted nanocarrier-based delivery Systems and
other advanced therapy medicinal products such as gene therapy
medicinal products (GTMPs), somatic cell therapy medicinal products
(sCTMPs), and tissue-engineered products (TEPs). In addition to
formulation aspects of biotechnology derived pharmaceuticals, it also
covers the application of polymers and excipients to solve
problems/issues concerning the optimization of absorption, selective
transport, and targeting.
PT 708 - Biopharmaceutics & Pharmacokinetics: (2+1)
The course is concerned with the exploration and examination of the
physicochemical properties of drugs in the physiological environment
and their impact on product performance. It explores the principles of
biopharmaceutics and strategies for enhancing drug delivery and
bioavailability .Also it introduces the students to basic
pharmacokinetic parameters and mathematical aspects. General
principles of pharmacokinetic models are presented as they pertain to
the process of absorption, distribution and elimination of drugs in
humans and the significance of these processes in drug therapy. Topics
also emphasize linear and nonlinear metabolic clearance kinetics,
drug-drug interaction mechanisms and kinetics, in vitro-in vivo
predictions, pharmacogenetics and other sources of inter-individual
variability.
PT E09 - Veterinary Pharmacy (1+1)
The commonly used veterinary biological and pharmaceutical
preparations; general sanitary and management procedures for the
prevention and control of livestock diseases; a brief review of
infectious diseases and animal parasites, veterinary specific
nomenclature, medication safety skills in their practice
PT E10 - Advanced Pharmaceutical Technology (1+1)
This course is designed to provide students with various important
aspects of quality assurance, cGMP, quality audit, and process
validation; including regulatory and quality compliance as applied to
pharmaceutical industries. The students will also be provided with indepth knowledge in the organization and operation of the major departments of pharmaceutical companies, as well as ways of dealing
with regulatory and compliance issues. Additionally, the course will
provide advanced information on drug discovery & development
process, including INDA, NDA & ANDA, drug master file &
therapeutic equivalent codes. Other essential topics such as production
& operational management, production planning & control shall be
covered. In addition, various in-process quality control tests needed to
assess some sterile and non-sterile products shall also be discussed.
The course will also include pilot plant and scale up techniques,
design, construction and operation of clean rooms as well as recent
advances in packaging techniques for various pharmaceutical dosage
forms, including stability & regulatory aspects of packaging.
PT E11 - Medical Devices (1+1)
Medical device technology is a course that presents an introduction of
medical devices and procedures. We shall cover Minimally invasive
and open procedures, techniques and devices, including mechanical
and electrosurgical devices Manufacturing methods for catheters,
balloons, plastic and metal components Design of metal device
components including material selection and strength and deformation
adequacy using material properties and classical mechanics Selection
of insulation materials for and testing of electrosurgical devices.
Selection of medical plastics and design elements. Balloon and
catheter burst strength. Understanding of biocompatibility testing and
accelerated age testing, Device sterilization methods and testing.
PT E12 - Good Manufacturing Practices (1+1)
Good Manufacturing Practices are guidelines that provide a system of
processes, procedures, and documentation to assure the product
produced has the identity, strength, composition, quality, and purity
that it is represented to possess. Concepts, objectives and applicability,
general provisions, organization and personal, Building and facilities,
materials, equipment, production and process controls, packing and
labeling, control, distribution, laboratory controls, records and reports,
returned and salvaged drug products, repacking , inspections and
recalls.
PT E13 - Applied Industrial Pharmacy (1+1)
Good manufacturing practice regulations and quality assurance with
emphasis on process validation and sampling techniques.
PT E14 - Cosmetic Preparations (1+1)
Definition and concepts, classification, hair preparation, Idea
generation, formulation development, manufacturing considerations of
bath preparation, fragrance preparation, make-up preparation, nail
lacquers, shaving preparations, after-shave preparations, skin care,
anal hygiene products, antiperspirants and deodorants, quality control
tests and evaluation of cosmetic products.
PT E15 - Drug Metabolism and Transport (1+1)
Learn how advances in biomedicine hold the potential to revolutionize
drug development, drug treatments, and disease prevention: where are
we now, and what does the future hold? This course will present short
primers in genetics and mechanisms underlying variability in drug
responses. A series of case studies will be used to illustrate principles
of how genetics are being brought to bear on refining diagnoses and on
personalizing treatment in rare and common diseases. The ethical and
operational issues around how to implement large scale genomic
sequencing in clinical practice will be addressed.
PT E16 - Protein Pharmaceuticals (1+1)
A perspective on the importance of formulation development in the
biopharmaceutical industry, An understanding of the most common
mechanisms of protein degradation, An overview of where
pharmaceutical macromolecules are most likely to be damaged during
handling and storage, The physical basis for the aggregation and
solubility behaviour of polypeptides, Descriptions of the most
important analytical tools needed in formulation development,
Detailed strategies for stabilization of peptide proteins and chemically
modified proteins. Overview of Formulation Development and
Principles of Proteins Stabilization, Introduction to Protein Structure
and Physical Properties, Overview of Instability Issues with Proteins.