General Program Courses - Pharm D

PMC 501 - Medicinal Chemistry I (2+1)
This course is tailored to assist the students to gain the drugs affecting the autonomic nervous system (ANS), drugs acting on the cardiovascular system (CVS), CNS. The course handles different classes of antibiotics and antimicrobials (natural and synthetic), beside other synthetic chemotherapeutic agents (including antivirals, antifungals and antiparasitics). Additionally, various anticancer therapies, steroidal hormones and related drugs are also covered.

PMC 602 - Medicinal Chemistry II (2+1)
The course is tailored to assist the students to gain the drugs affecting neurodegenerative disorders. Moreover, endocrine-related drugs (Diabetes, thyroid and calcium-regulating agents), antihistamines (H1, H2 blockers and anti-ulcer PPIs), drugs controlling pain and inflammation (NSAIDs, local anaesthetics and rheumatoid drugs) are also handled.

PMC 703 - Drug Design (1+1)
The prime objective of this course is to prepare the students for professional practice by understanding the essentials of Medicinal Chemistry, and how the drugs, biological and toxicological activities are strongly correlated to their chemical structures (Structure-activity relationship; SAR), physicochemical properties and metabolic pathways. Focusing on patient-directed clinical care, the molecular aspects governing drugs’ pharmacokinetics (ADME), pharmacodynamics, optimization of drug action, possible side effects, in addition to understanding drug interactions are targeted. In terms of chemistry, SAR, mechanism of action and side effects. The course is also designed to familiarize the students with drug design and molecular modelling covering structure-based and ligand-based drug design. This also includes the process of drug discovery and development from target identification until approval of a new drug. Much concern is given to lead structure identification, optimization and targeting certain receptors and enzymes active sites. Additionally, the course addresses the study of molecular docking, pharmacophore generation, and molecular modifications including prodrug design, stereochemistry alterations, isosteric replacement, drug metabolism and Quantitative Structure-activity relationship (QSAR).