Clinical Program Courses - PharmD

PB 301 - Biochemistry I ( 2 + 1 )
Structure of proteins – Biologically active peptides – Protein turnover – Amino acids as precursors for biosynthesis of biomolecules (e.g. neurotransmitters –nucleotides, …) – Structurally and physiologically important lipids – Lipoprotein metabolism – Carbohydrates and connective tissue – Enzymes (theories of enzyme action – enzyme kinetics – inhibition and regulation of enzyme activity – clinical correlations) – ATP synthesis from reduced metabolites (electron transport chain – inhibitors – uncouplers) – Hemoglobin and myoglobin (structure – synthesis and metabolism – clinical correlations).

PB 402 - Biochemistry II ( 2 + 1 )
Mobilization of body stores of glycogen and fats -Metabolism and tissue utilization of glucose, amino acids, and fatty acids – Regulation of blood glucose level and clinical correlations – Feed/fast cycle – Nitrogen metabolism and nitrogen balance – Inborn errors of metabolism – Second messengers and signal transduction – Biochemistry of cancer - Biochemistry of aging – Food biochemistry (milk – probiotics) – Oxidative stress and body defense mechanisms.

PB 803 - Clinical Biochemistry ( 2 + 1 )
Organ function and laboratory diagnostic tests (liver – kidney – heart – pancreas – bone) – Plasma proteins and albumin/globulin ratio – Types and lab differentiation of hyperlipidemia - Examples of different diseases (case study – interpretation of analytical data) - Handling, preservation, storage and analysis of biological samples - Abnormalities of urine analysis – Blood analysis and complete blood count – Tumor markers – Endocrinology (classification of hormones - mechanisms of action – dysfunction) - Electrolytes, blood gases and acid-base balance - Recent diagnostic biomarkers.